Afadin couples RAS GTPases to the polarity rheostat Scribble

Goudreault et al. investigate the role of Afadin downstream of RAS GTPases, substantiating this cell adhesion protein as a true RAS effector that couples its activation to cell polarity through the Scribble protein.

Bibliographic Details
Main Authors: Marilyn Goudreault, Valérie Gagné, Chang Hwa Jo, Swati Singh, Ryan C. Killoran, Anne-Claude Gingras, Matthew J. Smith
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32335-8