Newly identified breast luminal progenitor and gestational stem cell populations likely give rise to HER2-overexpressing and basal-like breast cancers

Abstract Breast Cancer (BrC) is a common malignancy with genetically diverse subtypes. There is evidence that specific BrC subtypes originate from particular normal mammary cell populations. However, the cell populations that give rise to most BrC subtypes are unidentified. Several human breast scRN...

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Bibliographic Details
Main Authors: James R. W. McMullen, Ubaldo Soto
Format: Article
Language:English
Published: Springer 2022-05-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-022-00500-6