Nicotine regulates PCSK9 expression in HepG2 cells through Raf/MEK/ERK signaling pathway
Objective To investigate the effect of nicotine (NIC) on the expression of proprotein convertase subtilisin/kexin type 9 (PCSK9) and its molecular mechanism. Methods Different concentrations of NIC (0, 5, 10 and 20 μmol/L) were used to treat HepG2 cells for 0, 24 or 48 h to observe the change of PCS...
Main Authors: | , , , , |
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Format: | Article |
Language: | zho |
Published: |
Editorial Office of Journal of Army Medical University
2023-07-01
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Series: | 陆军军医大学学报 |
Subjects: | |
Online Access: | http://aammt.tmmu.edu.cn/html/202301028.htm |