Low dissolved oxygen supply functions as a global regulator of the growth and metabolism of Aurantiochytrium sp. PKU#Mn16 in the early stages of docosahexaenoic acid fermentation

Abstract Background Thraustochytrids accumulate lipids with a high content of docosahexaenoic acid (DHA). Although their growth and DHA content are significantly affected by the dissolved oxygen (DO) supply, the role of DO on the transcriptional regulation of metabolism and accumulation of intracell...

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Bibliographic Details
Main Authors: Lu Liu, Xingyu Zhu, Huike Ye, Yingying Wen, Biswarup Sen, Guangyi Wang
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Microbial Cell Factories
Subjects:
Online Access:https://doi.org/10.1186/s12934-023-02054-w