A myristoyl switch at the plasma membrane triggers cleavage and oligomerization of Mason-Pfizer monkey virus matrix protein

A myristoyl switch at the plasma membrane triggers cleavage and oligomerization of Mason-Pfizer monkey virus matrix protein

For most retroviruses, including HIV, association with the plasma membrane (PM) promotes the assembly of immature particles, which occurs simultaneously with budding and maturation. In these viruses, maturation is initiated by oligomerization of polyprotein precursors. In contrast, several retroviru...

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Bibliographic Details
Main Authors: Markéta Častorálová, Jakub Sýs, Jan Prchal, Anna Pavlů, Lucie Prokopová, Zina Briki, Martin Hubálek, Tomas Ruml
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-03-01
Series:eLife
Subjects:
myristoyl switch
betaretrovirus
matrix protein
protease
maturation
Online Access:https://elifesciences.org/articles/93489

Internet

https://elifesciences.org/articles/93489

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