Conditional Ablation of Myeloid TNF Improves Functional Outcome and Decreases Lesion Size after Spinal Cord Injury in Mice

Conditional Ablation of Myeloid TNF Improves Functional Outcome and Decreases Lesion Size after Spinal Cord Injury in Mice

Spinal cord injury (SCI) is a devastating condition consisting of an instant primary mechanical injury followed by a secondary injury that progresses for weeks to months. The cytokine tumor necrosis factor (TNF) plays an important role in the pathophysiology of SCI. We investigated the effect of mye...

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Bibliographic Details
Main Authors: Ditte Gry Ellman, Minna Christiansen Lund, Maiken Nissen, Pernille Sveistrup Nielsen, Charlotte Sørensen, Emilie Boye Lester, Estrid Thougaard, Louise Helskov Jørgensen, Sergei A. Nedospasov, Ditte Caroline Andersen, Jane Stubbe, Roberta Brambilla, Matilda Degn, Kate Lykke Lambertsen
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
tumor necrosis factor
spinal cord injury
myeloid cells
functional outcome
Online Access:https://www.mdpi.com/2073-4409/9/11/2407

Internet

https://www.mdpi.com/2073-4409/9/11/2407

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