Disruption of the NF-κB/IκBα Autoinhibitory Loop Improves Cognitive Performance and Promotes Hyperexcitability of Hippocampal Neurons

<p>Abstract</p> <p>Background</p> <p>Though originally discovered in the immune system as an important mediator of inflammation, NF-κB has recently been shown to play key roles in the central nervous system, such as synaptogenesis, synaptic plasticity, and cognition. NF...

Full description

Bibliographic Details
Main Authors: Noebels Jeffrey L, Reed J, Yang Li, Shim David J, Chiao Paul J, Zheng Hui
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/6/1/42