Disruption of the NF-κB/IκBα Autoinhibitory Loop Improves Cognitive Performance and Promotes Hyperexcitability of Hippocampal Neurons
<p>Abstract</p> <p>Background</p> <p>Though originally discovered in the immune system as an important mediator of inflammation, NF-κB has recently been shown to play key roles in the central nervous system, such as synaptogenesis, synaptic plasticity, and cognition. NF...
Main Authors: | Noebels Jeffrey L, Reed J, Yang Li, Shim David J, Chiao Paul J, Zheng Hui |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-06-01
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Series: | Molecular Neurodegeneration |
Online Access: | http://www.molecularneurodegeneration.com/content/6/1/42 |
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