The type-2 Streptococcus canis M protein SCM-2 binds fibrinogen and facilitates antiphagocytic properties

The type-2 Streptococcus canis M protein SCM-2 binds fibrinogen and facilitates antiphagocytic properties

Streptococcus canis is a zoonotic agent that causes severe invasive diseases in domestic animals and humans, but little is known about its pathogenesis and virulence mechanisms so far. SCM, the M-like protein expressed by S. canis, is considered one of the major virulence determinants. Here, we repo...

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Bibliographic Details
Main Authors: Antje-Maria Lapschies, Etienne Aubry, Thomas P. Kohler, Oliver Goldmann, Sven Hammerschmidt, Andreas Nerlich, Inga Eichhorn, Kira van Vorst, Marcus Fulde
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Microbiology
Subjects:
Streptococcus canis
SCM
fibrinogen-binding
anti-phagocytosis
pathogen-host interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1228472/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1228472/full

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