Consumption of ultra-processed foods and risk for Alzheimer’s disease: a systematic review
ObjectiveTo investigate the association of the consumption of ultra-processed foods with the risk of developing Alzheimer’s disease in adults and the elderly. The review protocol was registered on PROSPERO (CRD42022375944).MethodsThis is a systematic review reported according to PRISMA guidelines. O...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2023.1288749/full |
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| author | Paola Alves Claudino Nassib Bezerra Bueno Sabrina Piloneto Dieniffer Halaiko Leticia Priscila Azevedo de Sousa Cassia Helena Barroso Jara Maia Bárbara Dal Molin Netto |
| author_facet | Paola Alves Claudino Nassib Bezerra Bueno Sabrina Piloneto Dieniffer Halaiko Leticia Priscila Azevedo de Sousa Cassia Helena Barroso Jara Maia Bárbara Dal Molin Netto |
| author_sort | Paola Alves Claudino |
| collection | DOAJ |
| description | ObjectiveTo investigate the association of the consumption of ultra-processed foods with the risk of developing Alzheimer’s disease in adults and the elderly. The review protocol was registered on PROSPERO (CRD42022375944).MethodsThis is a systematic review reported according to PRISMA guidelines. Observational studies were included without language or publication year restrictions. Studies assessing only other types of dementia as outcomes, not considering Alzheimer’s disease, were excluded. The research was carried out in the Medline, Embase, Lilacs databases, and a survey of the gray literature between April and November 2023, in addition to citation search in the included studies. Data extraction was performed by two independent reviewers. The risk of bias and methodological quality of the included studies were assessed using the Joanna Briggs Institute checklist for cohort studies.ResultsA total of 5 studies involving 617,502 adults and elderly people were included. All studies had a cohort design and were considered of high methodological quality. Of the included studies, 4 demonstrated a risk association between the consumption of ultra-processed foods and the development of Alzheimer’s disease, while 1 study showed a risk association only with the development of cognitive decline.DiscussionThe association between ultra-processed foods consumption and the risk of developing Alzheimer’s disease is a recent topic in scientific studies, given that the oldest study identified by our review dates back to 2017. Of the four included studies, three showed a significant association between ultra-processed foods consumption and the risk of developing Alzheimer’s disease. |
| first_indexed | 2024-03-08T14:08:55Z |
| format | Article |
| id | doaj.art-585b8243b7f4449282ed1959171ed66e |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-03-08T14:08:55Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-585b8243b7f4449282ed1959171ed66e2024-01-15T04:19:54ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2024-01-011010.3389/fnut.2023.12887491288749Consumption of ultra-processed foods and risk for Alzheimer’s disease: a systematic reviewPaola Alves Claudino0Nassib Bezerra Bueno1Sabrina Piloneto2Dieniffer Halaiko3Leticia Priscila Azevedo de Sousa4Cassia Helena Barroso Jara Maia5Bárbara Dal Molin Netto6Postgraduation Program in Food and Nutrition, Federal University of Paraná, Curitiba, BrazilPostgraduation Program in Nutrition, Federal University of Alagoas, Maceió, BrazilPontifical Catholic University of Paraná, Curitiba, BrazilFederal University of Paraná, Curitiba, BrazilFederal University of Paraná, Curitiba, BrazilPostgraduation Program in Food and Nutrition, Federal University of Paraná, Curitiba, BrazilPostgraduation Program in Food and Nutrition, Department of Nutrition, Federal University of Paraná, Curitiba, BrazilObjectiveTo investigate the association of the consumption of ultra-processed foods with the risk of developing Alzheimer’s disease in adults and the elderly. The review protocol was registered on PROSPERO (CRD42022375944).MethodsThis is a systematic review reported according to PRISMA guidelines. Observational studies were included without language or publication year restrictions. Studies assessing only other types of dementia as outcomes, not considering Alzheimer’s disease, were excluded. The research was carried out in the Medline, Embase, Lilacs databases, and a survey of the gray literature between April and November 2023, in addition to citation search in the included studies. Data extraction was performed by two independent reviewers. The risk of bias and methodological quality of the included studies were assessed using the Joanna Briggs Institute checklist for cohort studies.ResultsA total of 5 studies involving 617,502 adults and elderly people were included. All studies had a cohort design and were considered of high methodological quality. Of the included studies, 4 demonstrated a risk association between the consumption of ultra-processed foods and the development of Alzheimer’s disease, while 1 study showed a risk association only with the development of cognitive decline.DiscussionThe association between ultra-processed foods consumption and the risk of developing Alzheimer’s disease is a recent topic in scientific studies, given that the oldest study identified by our review dates back to 2017. Of the four included studies, three showed a significant association between ultra-processed foods consumption and the risk of developing Alzheimer’s disease.https://www.frontiersin.org/articles/10.3389/fnut.2023.1288749/fullultraprocessed foodindustrialized foodfast-foodAlzheimer’s diseaseAlzheimer’s dementia |
| spellingShingle | Paola Alves Claudino Nassib Bezerra Bueno Sabrina Piloneto Dieniffer Halaiko Leticia Priscila Azevedo de Sousa Cassia Helena Barroso Jara Maia Bárbara Dal Molin Netto Consumption of ultra-processed foods and risk for Alzheimer’s disease: a systematic review Frontiers in Nutrition ultraprocessed food industrialized food fast-food Alzheimer’s disease Alzheimer’s dementia |
| title | Consumption of ultra-processed foods and risk for Alzheimer’s disease: a systematic review |
| title_full | Consumption of ultra-processed foods and risk for Alzheimer’s disease: a systematic review |
| title_fullStr | Consumption of ultra-processed foods and risk for Alzheimer’s disease: a systematic review |
| title_full_unstemmed | Consumption of ultra-processed foods and risk for Alzheimer’s disease: a systematic review |
| title_short | Consumption of ultra-processed foods and risk for Alzheimer’s disease: a systematic review |
| title_sort | consumption of ultra processed foods and risk for alzheimer s disease a systematic review |
| topic | ultraprocessed food industrialized food fast-food Alzheimer’s disease Alzheimer’s dementia |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2023.1288749/full |
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