Omics Technologies to Decipher Regulatory Networks in Granulocytic Cell Differentiation

Omics Technologies to Decipher Regulatory Networks in Granulocytic Cell Differentiation

Induced granulocytic differentiation of human leukemic cells under all-<i>trans</i>-retinoid acid (ATRA) treatment underlies differentiation therapy of acute myeloid leukemia. Knowing the regulation of this process it is possible to identify potential targets for antileukemic drugs and d...

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Bibliographic Details
Main Authors: Svetlana Novikova, Olga Tikhonova, Leonid Kurbatov, Tatiana Farafonova, Igor Vakhrushev, Alexey Lupatov, Konstantin Yarygin, Victor Zgoda
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomolecules
Subjects:
acute myeloid leukemia
HL-60 cell line
ATRA
induced differentiation
transcriptome
proteome
Online Access:https://www.mdpi.com/2218-273X/11/6/907

Internet

https://www.mdpi.com/2218-273X/11/6/907

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