Pulmonary midkine inhibition ameliorates sepsis induced lung injury

Abstract Background Midkine is a multi-functional molecule participating in a various key pathological process. We aimed to evaluate the change of midkine in sepsis and its association with angiotensin-converting enzyme (ACE) system, as well as the mechanism by which midkine induced in sepsis and lu...

Full description

Bibliographic Details
Main Authors: Jing-Yuan Xu, Wei Chang, Qin Sun, Fei Peng, Yi Yang
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-021-02755-z