Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium

Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium

Compartmentalization of cellular signaling forms the molecular basis of cellular behavior. The primary cilium constitutes a subcellular compartment that orchestrates signal transduction independent from the cell body. Ciliary dysfunction causes severe diseases, termed ciliopathies. Analyzing ciliary...

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Bibliographic Details
Main Authors: Jan N Hansen, Fabian Kaiser, Christina Klausen, Birthe Stüven, Raymond Chong, Wolfgang Bönigk, David U Mick, Andreas Möglich, Nathalie Jurisch-Yaksi, Florian I Schmidt, Dagmar Wachten
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
cyclic amp
cilia
optogenetics
Online Access:https://elifesciences.org/articles/57907

Internet

https://elifesciences.org/articles/57907

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