Multi-Omics Analyses Reveal Mitochondrial Dysfunction Contributing to Temozolomide Resistance in Glioblastoma Cells

Glioblastoma (GBM) is the most common and aggressive malignant brain tumor with poor prognosis. Temozolomide (TMZ) is the standard chemotherapy for glioblastoma treatment, but TMZ resistance significantly compromises its efficacy. In the present study, we generated a TMZ-resistant cell line and iden...

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מידע ביבליוגרפי
Main Authors: Huaijin Zhang, Yuling Chen, Xiaohui Liu, Haiteng Deng
פורמט: Article
שפה:English
יצא לאור: MDPI AG 2023-09-01
סדרה:Biomolecules
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גישה מקוונת:https://www.mdpi.com/2218-273X/13/9/1408