Prenatal diagnosis of a 4.5-Mb deletion at chromosome 4q35.1q35.2: Case report and literature review

Prenatal diagnosis of a 4.5-Mb deletion at chromosome 4q35.1q35.2: Case report and literature review

Abstract Objective We present a genetic analysis of an asymptomatic family with a 4q terminal deletion; we also review other similar published studies and discuss the genotype–phenotype correlation. Methods A karyotype analysis was performed on the amniotic fluid cells of a woman at 24 weeks of preg...

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Bibliographic Details
Main Authors: Gefei Xiao, Xianrong Qiu, Yuqiu Zhou, Gongjun Tan, Yao Shen
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Molecular Cytogenetics
Subjects:
Karyotype analysis
Prenatal diagnosis
Chromosome microarray analysis
Copy number variation
Online Access:https://doi.org/10.1186/s13039-021-00573-y

Internet

https://doi.org/10.1186/s13039-021-00573-y

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