Hypoxic regulation of the expression of cell proliferation related genes in U87 glioma cells upon inhibition of IRE1 signaling enzyme

We have studied the effect of inhibition of IRE1 (inositol requiring enzyme 1), which is a central mediator of endoplasmic reticulum stress and a controller of cell proliferation and tumor growth, on hypoxic regulation of the expression of different proliferation related genes in U87 glioma cells. I...

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Bibliographic Details
Main Authors: O. H. Minchenko, D. O. Tsymbal, D. O. Minchenko, O. O. Riabovol, O. O. Ratushna, L. L. Karbovskyi
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2017-02-01
Series:The Ukrainian Biochemical Journal
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2016/03/Minchenko_1_16.pdf