Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses

Abstract Background Acute lung injury (ALI) has received considerable attention in the field of intensive care as it is associated with a high mortality rate. Obacunone (OB), widely found in citrus fruits, is a natural bioactive compound with anti-inflammatory and antioxidant activities. However, it...

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Bibliographic Details
Main Authors: Jin Li, Shi-hua Deng, Jing Li, Li Li, Feng Zhang, Ye Zou, Dong-ming Wu, Ying Xu
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:https://doi.org/10.1186/s11658-022-00318-8