Coaction of spheroid-derived stem-like cells and endothelial progenitor cells promotes development of colon cancer.

Coaction of spheroid-derived stem-like cells and endothelial progenitor cells promotes development of colon cancer.

Although some studies described the characteristics of colon cancer stem cells (CSCs) and the role of endothelial progenitor cells (EPCs) in neovascularization, it is still controversial whether an interaction exists or not between CSCs and EPCs. In the present study, HCT116 and HT29 sphere models,...

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Bibliographic Details
Main Authors: Bo Wei, Xiao-Yan Han, Cui-Ling Qi, Shi Zhang, Zong-Heng Zheng, Yong Huang, Tu-Feng Chen, Hong-Bo Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3383752?pdf=render

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http://europepmc.org/articles/PMC3383752?pdf=render

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