Regulation of C3 Activation by the Alternative Complement Pathway in the Mouse Retina.

Regulation of C3 Activation by the Alternative Complement Pathway in the Mouse Retina.

The purpose of this study was to examine the retinas of mice carrying hemizygous and null double deletions of Cfb-/- and Cfh-/-, and to compare these with the single knockouts of Cfb, Cfh and Cfd. Retinas were isolated from wild type (WT), Cfb-/-/Cfh-/-, Cfb-/-/Cfh+/-, Cfh-/-/Cfb+/-, Cfb-/-, Cfh-/-...

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Bibliographic Details
Main Authors: Jennifer A E Williams, Dimitris Stampoulis, Chloe E Gunter, John Greenwood, Peter Adamson, Stephen E Moss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5001704?pdf=render

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http://europepmc.org/articles/PMC5001704?pdf=render

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