Cross-platform comparisons for targeted bisulfite sequencing of MGISEQ-2000 and NovaSeq6000

Cross-platform comparisons for targeted bisulfite sequencing of MGISEQ-2000 and NovaSeq6000

Abstract Background An accurate and reproducible next-generation sequencing platform is essential to identify malignancy-related abnormal DNA methylation changes and translate them into clinical applications including cancer detection, prognosis, and surveillance. However, high-quality DNA methylati...

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Bibliographic Details
Main Authors: Jin Sun, Mingyang Su, Jianhua Ma, Minjie Xu, Chengcheng Ma, Wei Li, Rui Liu, Qiye He, Zhixi Su
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Clinical Epigenetics
Subjects:
Targeted bisulfite sequencing
cfDNA
MGISEQ-2000
Methylation
ctDNA
NGS
Online Access:https://doi.org/10.1186/s13148-023-01543-4

Internet

https://doi.org/10.1186/s13148-023-01543-4

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