436 Examining the Role of Obesity and Leptin Signaling in Triple Negative Breast Cancer
OBJECTIVES/GOALS: In triple negative breast cancer (TNBC), obesity is associated with poor outcomes. Adipose stem cells (ASCs) from obese patients (obASCs) secrete higher levels of adipokines compared to ASCs from lean individuals. Leptin, one of these adipokines, has been implicated in many cancers...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Cambridge University Press
2022-04-01
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Series: | Journal of Clinical and Translational Science |
Online Access: | https://www.cambridge.org/core/product/identifier/S2059866122002540/type/journal_article |