FUBP1 promotes neuroblastoma proliferation via enhancing glycolysis-a new possible marker of malignancy for neuroblastoma

FUBP1 promotes neuroblastoma proliferation via enhancing glycolysis-a new possible marker of malignancy for neuroblastoma

Abstract Background Neuroblastoma (NB) is one of the deadliest paediatric solid tumours due to its rapid proliferative characteristics. Amplified copies of MYCN are considered the most important marker for the prediction of tumour relapse and progression in NB, but they were only detected in 20–30%...

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Bibliographic Details
Main Authors: Ping Jiang, Mao Huang, Weiwei Qi, Fenghua Wang, Tianyou Yang, Tianxiao Gao, Chuanghua Luo, Jing Deng, Zhonghan Yang, Ti Zhou, Yan Zou, Guoquan Gao, Xia Yang
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
FUBP1
Neuroblastoma
Glycolysis
C-Myc
HIF1α
VHL
Online Access:http://link.springer.com/article/10.1186/s13046-019-1414-6

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http://link.springer.com/article/10.1186/s13046-019-1414-6

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