General Anaesthesia Shifts the Murine Circadian Clock in a Time-Dependant Fashion

General Anaesthesia Shifts the Murine Circadian Clock in a Time-Dependant Fashion

Following general anaesthesia (GA), patients frequently experience sleep disruption and fatigue, which has been hypothesized to result at least in part by GA affecting the circadian clock. Here, we provide the first comprehensive time-dependent analysis of the effects of the commonly administered in...

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Bibliographic Details
Main Authors: Nicola M. Ludin, Alma Orts-Sebastian, James F. Cheeseman, Janelle Chong, Alan F. Merry, David Cumin, Shin Yamazaki, Matthew D. M. Pawley, Guy R. Warman
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Clocks & Sleep
Subjects:
general anaesthesia
circadian clock
phase response curve
PERIOD2::LUC
clock gene
Online Access:https://www.mdpi.com/2624-5175/3/1/6

Internet

https://www.mdpi.com/2624-5175/3/1/6

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