Pharmacological Blockade of Adenosine A2A but Not A1 Receptors Enhances Goal-Directed Valuation in Satiety-Based Instrumental Behavior

Pharmacological Blockade of Adenosine A2A but Not A1 Receptors Enhances Goal-Directed Valuation in Satiety-Based Instrumental Behavior

The balance and smooth shift between flexible, goal-directed behaviors and repetitive, habitual actions are critical to optimal performance of behavioral tasks. The striatum plays an essential role in control of goal-directed versus habitual behaviors through a rich interplay of the numerous neurotr...

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Bibliographic Details
Main Authors: Yan Li, Xinran Pan, Yan He, Yang Ruan, Linshan Huang, Yuling Zhou, Zhidong Hou, Chaoxiang He, Zhe Wang, Xiong Zhang, Jiang-Fan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Pharmacology
Subjects:
adenosine A2A receptor
adenosine A1 receptor
goal-directed behavior
habit
instrumental behavior
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00393/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00393/full

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