Gut microbe-derived metabolite trimethylamine N-oxide activates the cardiac autonomic nervous system and facilitates ischemia-induced ventricular arrhythmia via two different pathwaysResearch in context

Gut microbe-derived metabolite trimethylamine N-oxide activates the cardiac autonomic nervous system and facilitates ischemia-induced ventricular arrhythmia via two different pathwaysResearch in context

Background: We previously demonstrated the gut microbes-derived metabolite trimethylamine N-oxide (TMAO) could activate the atrial autonomic ganglion plexus and promote atrial arrhythmia. The cardiac sympathetic nervous system (CSNS) play important roles in modulating ventricular arrhythmia (VA). Me...

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Bibliographic Details
Main Authors: Guannan Meng, Xiaoya Zhou, Menglong Wang, Liping Zhou, Zhenya Wang, Meng Wang, Jielin Deng, Yuhong Wang, Zhen Zhou, Yifeng Zhang, Yanqiu Lai, Qianqian Zhang, Xiaomeng Yang, Lilei Yu, Hong Jiang
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419302117

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http://www.sciencedirect.com/science/article/pii/S2352396419302117

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