Inactivated and Immunogenic SARS-CoV-2 for Safe Use in Immunoassays and as an Immunization Control for Non-Clinical Trials

Successful SARS-CoV-2 inactivation allows its safe use in Biosafety Level 2 facilities, and the use of the whole viral particle helps in the development of analytical methods and a more reliable immune response, contributing to the development and improvement of in vitro and in vivo assays. In order...

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Main Authors: Mariana Pierre de Barros Gomes, José Henrique Rezende Linhares, Tiago Pereira dos Santos, Renata Carvalho Pereira, Renata Tourinho Santos, Stephanie Almeida da Silva, Marta Cristina de Oliveira Souza, Juliana Fernandes Amorim da Silva, Gisela Freitas Trindade, Viviane Silva Gomes, Débora Ferreira Barreto-Vieira, Milena Mouta Verdan França Carvalho, Ana Paula Dinis Ano Bom, Noemi Rovaris Gardinali, Rodrigo Müller, Nathalia dos Santos Alves, Luma da Cruz Moura, Patrícia Cristina da Costa Neves, Gabriela Santos Esteves, Waleska Dias Schwarcz, Sotiris Missailidis, Ygara da Silva Mendes, Sheila Maria Barbosa de Lima
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/7/1486