Estrogen inhibits colonic smooth muscle contractions by regulating BKβ1 signaling.

The estrogen inhibits colonic smooth muscle contractions, which may lead to constipation. However, the mechanisms of inhibition are poorly understood. Therefore, the present study examined the effect of estrogen on rat colonic smooth muscle contractions and its potential association with the large-c...

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Bibliographic Details
Main Authors: Jing Wen, Yu Zhao, Cheng Huang, Shengjie Li, Peidong Li, Yu Zhou, Zaihua Yan, Guangjun Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0294249