A protocol to differentiate nociceptors, mechanoreceptors, and proprioceptors from human pluripotent stem cells

Summary: Human pluripotent stem cells (hPSCs) show promise for studying diseases affecting cell populations that are not easily available, including sensory neurons (SNs). Here, we present a differentiation protocol in chemically defined conditions to generate peripheral SNs from hPSCs. We describe...

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Bibliographic Details
Main Authors: Kenyi Saito-Diaz, Nadja Zeltner
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722000673