The effect of cyclooxygenase-2 inhibition on pentylenetetrazole-induced seizure threshold in mice

Background: Previous studies have shown the protective effect of cyclooxygenase (COX) enzyme in development of convulsions. However, involvement of COX-2 in the pathogenesis of epilepsy is not yet well-known. The present study was designed to investigate the effect of celecoxib and nimesulide (selec...

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Bibliographic Details
Main Authors: Azam Mesdaghinia, Paria Khazaee, Azhdar Heydari
Format: Article
Language:fas
Published: Kashan University of Medical Sciences and Health Services 2018-08-01
Series:Fiyz̤
Subjects:
Online Access:http://feyz.kaums.ac.ir/article-1-3599-en.html