Evaluation of Novel Oral Vaccine Candidates and Validation of a Caprine Model of Johne's Disease

Evaluation of Novel Oral Vaccine Candidates and Validation of a Caprine Model of Johne's Disease

Johne’s disease (JD) caused by Mycobacterium avium subspecies paratuberculosis (MAP) is a major threat to the dairy industry and possibly some cases of Crohn’s disease in humans. A MAP vaccine that reduced of clinical disease and/or reduced fecal shedding would aid in the control of JD. The objecti...

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Bibliographic Details
Main Authors: Murray E. Hines, Sue E. Turquist, Marcia R. S. Ilha, Sreekumari eRajeev, Arthur Lee Jones, Lisa eWhittington, John P. Bannantine, Raul G. Barletta, Yrjo T. Grohn, Robab Marjan Katani, Adel M Talaat, Lingling eLi, Vivek eKapur
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Goats
vaccine efficacy
Mycobacterium avium subsp paratuberculosis
mutant vaccines
diagnostic tests
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00026/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00026/full

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