Lnc-PSMA8-1 activated by GEFT promotes rhabdomyosarcoma progression via upregulation of mTOR expression by sponging miR-144-3p

Lnc-PSMA8-1 activated by GEFT promotes rhabdomyosarcoma progression via upregulation of mTOR expression by sponging miR-144-3p

Abstract Background GEFT is a key regulator of tumorigenesis in rhabdomyosarcoma (RMS), and overexpression of GEFT is significantly correlated with distant metastasis, lymph node metastasis, and a poor prognosis, yet the underlying molecular mechanism is still poorly understood. This study aimed to...

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Bibliographic Details
Main Authors: Lian Meng, Hao Shang, Qianqian Liu, Zhenzhen Li, Xiaomeng Wang, Qianru Li, Feng Li, Zhenguo Zhao, Chunxia Liu
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Cancer
Subjects:
Rhabdomyosarcoma
ceRNA
GEFT
lnc-PSMA8-1
miR-144-3p
mTOR
Online Access:https://doi.org/10.1186/s12885-023-11798-y

Internet

https://doi.org/10.1186/s12885-023-11798-y

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