Optimization of probiotic therapeutics using machine learning in an artificial human gastrointestinal tract

Abstract The gut microbiota’s metabolome is composed of bioactive metabolites that confer disease resilience. Probiotics’ therapeutic potential hinges on their metabolome altering ability; however, characterizing probiotics’ metabolic activity remains a formidable task. In order to solve this proble...

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Bibliographic Details
Main Authors: Susan Westfall, Francesca Carracci, Molly Estill, Danyue Zhao, Qing-li Wu, Li Shen, James Simon, Giulio Maria Pasinetti
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79947-y