Efficacy of Integrated Social Cognitive Remediation vs. Neurocognitive Remediation in Improving Functional Outcome in Schizophrenia: Concept and Design of a Multicenter, Single-Blind RCT (The ISST Study)

BackgroundAlthough clinically effective treatment is available for schizophrenia, recovery often is still hampered by persistent poor psychosocial functioning, which in turn is limited by impairments in neurocognition, social cognition, and social behavioral skills. Although cognitive remediation ha...

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Main Authors: Wolfgang Wölwer, Nicole Frommann, Agnes Lowe, Daniel Kamp, Karolin Weide, Andreas Bechdolf, Anke Brockhaus-Dumke, Rene Hurlemann, Ana Muthesius, Stefan Klingberg, Martin Hellmich, Sabine Schmied, Andreas Meyer-Lindenberg, For the ISST study group, W. Wölwer, S. Abresch, N. Frommann, A. Lowe, D. Kamp, P. Ockenfelds, K. Weide, F. Pessanha, S. Dinse (Düsseldorf);, A. Philipsen, R. Hurlemann, J. Schultz, N. Striepens, U. Darrelmann, C. Kloss, S. Wasserthal, H. Högenauer, N. Schumacher (Bonn);, F. Jessen, J. Kambeitz, C. Baldermann, A. Muthesius, C. Doll, H. Schneegans, A. Ferrari, G. Kolb, T. Haidl, D. Zeus, T. Pilgram, M. Rohde, P. Albert-Porcar, S. Hölzer, M. Hellmich, K. Kuhr, K. Rosenberger, D. Kraus, S. Schmied, U. Bergmann, F. Scheckenbach, A. Montada (Cologne);, S. Klingberg, D. Wildgruber, U. Hermanutz, J. Richter, J. Vonderschmitt, L. Hölz (Tübingen);, A. Bechdolf, K. Leopold, S. Siebert, F. Seidel, E.S. Blanke (Berlin), A. Brockhaus-Dumke, X. Solojenkina, B. Klos, E. Rosenbauer, S. Cinar, L. Herdt, F. Henrich, S. Neff (Alzey), A. Meyer-Lindenberg (Mannheim)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Psychiatry
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Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.909370/full