Recurrent loss of CenH3 is associated with independent transitions to holocentricity in insects

Faithful chromosome segregation in all eukaryotes relies on centromeres, the chromosomal sites that recruit kinetochore proteins and mediate spindle attachment during cell division. The centromeric histone H3 variant, CenH3, is the defining chromatin component of centromeres in most eukaryotes, incl...

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Bibliographic Details
Main Authors: Ines A Drinnenberg, Dakota deYoung, Steven Henikoff, Harmit Singh Malik
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/03676