Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)

Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)

Abstract Background With declining wild fish populations, farmed salmon has gained popularity as a source for healthy long-chain highly unsaturated fatty acids (LC-HUFA). However, the introduction of plant oil in farmed salmon feeds has reduced the content of these beneficial LC-HUFA. The synthetic...

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Bibliographic Details
Main Authors: Yang Jin, Alex K. Datsomor, Rolf E. Olsen, Jon Olav Vik, Jacob S. Torgersen, Rolf B. Edvardsen, Anna Wargelius, Per Winge, Fabian Grammes
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Genomics
Subjects:
Atlantic salmon
CRISPR mosaicism
Long-chain highly unsaturated fatty acids
Fatty acid desaturase
Sterol regulatory binding protein, exon skipping
Transcriptional regulation
Online Access:http://link.springer.com/article/10.1186/s12864-020-07218-1

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http://link.springer.com/article/10.1186/s12864-020-07218-1

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