Genome-scale annotation of protein binding sites via language model and geometric deep learning
Revealing protein binding sites with other molecules, such as nucleic acids, peptides, or small ligands, sheds light on disease mechanism elucidation and novel drug design. With the explosive growth of proteins in sequence databases, how to accurately and efficiently identify these binding sites fro...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2024-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/93695 |