Acute promyelocytic leukemia with JAK2 V617F and severe differentiation syndrome

Myeloproliferative neoplasms transformed into AML usually have a poor prognosis. We report a case of essential thrombocythemia with myelofibrosis that transformed into acute promyelocytic leukemia (APL) with both the t(15;17) translocation as well as the JAK2 V617F mutation. Clinically, this case wa...

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Bibliographic Details
Main Authors: Theodore P. Braun, Julia E. Maxson, Anupriya Agarwal, Jennifer Dunlap, Stephen E. Spurgeon, Elie Traer
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Leukemia Research Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048914200203