Identification of 3-Methoxycarpachromene and Masticadienonic Acid as New Target Inhibitors against Trypanothione Reductase from <i>Leishmania Infantum</i> Using Molecular Docking and ADMET Prediction

Identification of 3-Methoxycarpachromene and Masticadienonic Acid as New Target Inhibitors against Trypanothione Reductase from <i>Leishmania Infantum</i> Using Molecular Docking and ADMET Prediction

Polyphenolic and Terpenoids are potent natural antiparasitic compounds. This study aimed to identify new drug against Leishmania parasites, leishmaniasis’s causal agent. A new in silico analysis was accomplished using molecular docking, with the Autodock vina program, to find the binding affinity of...

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Bibliographic Details
Main Authors: Sarra Maamri, Khedidja Benarous, Mohamed Yousfi
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
leishmania parasites
trypanothione reductase
masticadienonic acid
3-methoxycarpachromene
molecular docking
ADMET study
Online Access:https://www.mdpi.com/1420-3049/26/11/3335

Internet

https://www.mdpi.com/1420-3049/26/11/3335

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