Low IL7R Expression at Diagnosis Predicted Relapse in Adult Acute Myeloid Leukemia Patients With t(8;21)

Low IL7R Expression at Diagnosis Predicted Relapse in Adult Acute Myeloid Leukemia Patients With t(8;21)

BackgroundAcute myeloid leukemia (AML) with t(8;21) needs to be further stratified. In addition to leukemia cells, immune cells in tumor microenvironment participate in tumor initiation, growth and progression. Interleukins (ILs)/interleukin receptors (ILRs) interaction plays important roles in the...

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Bibliographic Details
Main Authors: Nan Xu, Kai Sun, Ya-Zhe Wang, Wen-Min Chen, Jun Wang, Ling-Di Li, Xu Wang, Yue Hao, Yan Chang, Yan-Rong Liu, Xiao-Jun Huang, Ya-Zhen Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
t(8;21) AML
IL7R
relapse
real-time quantitative PCR
RNAseq
flow cytometry
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.909104/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.909104/full

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