Development of a novel cognitive composite outcome to assess therapeutic effects of exercise in the EXERT trial for adults with MCI: The ADAS‐Cog‐Exec

Development of a novel cognitive composite outcome to assess therapeutic effects of exercise in the EXERT trial for adults with MCI: The ADAS‐Cog‐Exec

Abstract Introduction Use of cognitive composites as primary outcome measures is increasingly common in clinical trials of preclinical and prodromal Alzheimer's disease (AD). Composite outcomes can decrease intra‐individual variability, resulting in improved sensitivity to detect longitudinal c...

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Bibliographic Details
Main Authors: Diane M. Jacobs, Ronald G. Thomas, David P. Salmon, Shelia Jin, Howard H. Feldman, Carl W. Cotman, Laura D. Baker, for the Alzheimer's Disease Cooperative Study EXERT Study Group, for the Alzheimer's Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
aerobic exercise, Alzheimer's disease, cognition
composite outcome, mild cognitive impairment, randomized controlled trial
Online Access:https://doi.org/10.1002/trc2.12059

Internet

https://doi.org/10.1002/trc2.12059

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