Field trial of efficacy of the Leish-tec® vaccine against canine leishmaniasis caused by Leishmania infantum in an endemic area with high transmission rates.

Because domestic dogs are reservoir hosts for visceral leishmaniasis (VL) in Brazil, one of the approaches used to reduce human disease incidence is to cull infected dogs. However, the results of controlled intervention trials based on serological screening of dogs and killing of seropositive animal...

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Bibliographic Details
Main Authors: Gabriel Grimaldi, Antonio Teva, Claudiney B Dos-Santos, Fernanda Nunes Santos, Israel de-Souza Pinto, Blima Fux, Gustavo Rocha Leite, Aloísio Falqueto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5617193?pdf=render