Inflammasome NLRP3 activation induced by Convulxin, a C-type lectin-like isolated from Crotalus durissus terrificus snake venom

Inflammasome NLRP3 activation induced by Convulxin, a C-type lectin-like isolated from Crotalus durissus terrificus snake venom

Abstract Convulxin (CVX), a C-type lectin-like protein isolated from the venom of the snake species, Crotalus durissus terrificus, stimulates platelet aggregation by acting as a collagen receptor agonist for glycoprotein VI found in the platelets. The effect of CVX on platelets has been studied, but...

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Bibliographic Details
Main Authors: Cristina M. A. Rego, Aleff F. Francisco, Charles N. Boeno, Mauro V. Paloschi, Jéssica A. Lopes, Milena D. S. Silva, Hallison M. Santana, Suzanne N. Serrath, Jaína E. Rodrigues, Caleb T. L. Lemos, Ricardo S. S. Dutra, Jorddy N. da Cruz, Cleydson Breno R. dos Santos, Sulamita da S. Setúbal, Marcos R. M. Fontes, Andreimar M. Soares, Weverson L. Pires, Juliana P. Zuliani
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08735-7

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https://doi.org/10.1038/s41598-022-08735-7

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