Dissimilarity in the folding of human cytosolic creatine kinase isoenzymes.

Creatine kinase (CK, EC 2.7.3.2) plays a key role in the energy homeostasis of excitable cells. The cytosolic human CK isoenzymes exist as homodimers (HMCK and HBCK) or a heterodimer (MBCK) formed by the muscle CK subunit (M) and/or brain CK subunit (B) with highly conserved three-dimensional struct...

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Bibliographic Details
Main Authors: Yin Wang, Sha Wang, Yan-Song Gao, Zhe Chen, Hai-Meng Zhou, Yong-Bin Yan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3170377?pdf=render