Post-transcriptional capping generates coenzyme A-linked RNA

Post-transcriptional capping generates coenzyme A-linked RNA

NAD can be inserted co-transcriptionally via non-canonical initiation to form NAD-RNA. However, that mechanism is unlikely for CoA-linked RNAs due to low intracellular concentration of the required initiator nucleotide, 3’-dephospho-CoA (dpCoA). We report here that phosphopantetheine adenylyltransfe...

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Bibliographic Details
Main Authors: Krishna Sapkota, Jordyn K. Lucas, Jarrett W. Faulkner, Matt F. Lichte, Yan-Lin Guo, Donald H. Burke, Faqing Huang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:RNA Biology
Subjects:
CoA-RNA
PPAT
post-transcriptional CoA-capping
cofactor-RNA conjugates
CoA-RNA CaptureSeq
Online Access:https://www.tandfonline.com/doi/10.1080/15476286.2023.2288740

Internet

https://www.tandfonline.com/doi/10.1080/15476286.2023.2288740

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