Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction

Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction

Notoginsenoside R1 (NGR1) is the main monomeric component extracted from the dried roots and rhizomes of Panax notoginseng, and exerts pharmacological action against myocardial infarction (MI). Owing to the differences in compound distribution, absorption, and metabolism in vivo, exploring a more ef...

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Bibliographic Details
Main Authors: Han Li, Jing Zhu, Yan-wu Xu, Fang-fang Mou, Xiao-li Shan, Qiang-li Wang, Bao-nian Liu, Ke Ning, Jia-jia Liu, Ya-chao Wang, Jin-xia Mi, Xiaohui Wei, Shui-jin Shao, Guo-hong Cui, Rong Lu, Hai-dong Guo
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Redox Biology
Subjects:
Myocardial infarction
Notoginsenoside R1
Mesoporous silica nanoparticles
PI3K/AKT signaling pathway
MAPK signaling pathway
Hippo signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001562

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http://www.sciencedirect.com/science/article/pii/S2213231722001562

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