PRIMARY INFERTILITY, OXIDATIVE STRESS AND METFORMIN; IMPACT ON PRIMARY HUMAN GRANULOSA CELL CULTURES

PRIMARY INFERTILITY, OXIDATIVE STRESS AND METFORMIN; IMPACT ON PRIMARY HUMAN GRANULOSA CELL CULTURES

OBJECTIVE: To observe the effect of metformin on oxidative stress (OS) levels and SIRT1 expression in primary human granulosa cell cultures from infertile females. METHODS: This cross-sectional study was conducted from August 2017–July 2019 on ten infertile patients after approval from Ethical Re...

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Bibliographic Details
Main Authors: Faiza Alam, Rehana Rehman, Nida Farooqi, Farrukh Jehan, Syed Hani Abidi
Format: Article
Language:English
Published: Khyber Medical University 2021-11-01
Series:Khyber Medical University Journal
Subjects:
infertility
antioxidants
infertility female
oxidative stress
human granulosa cells
sirt1
sirtuins
primary cell cultures
metformin
sirtuin 1
Online Access:https://www.kmuj.kmu.edu.pk/article/view/22220

Internet

https://www.kmuj.kmu.edu.pk/article/view/22220

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