Shionone Attenuates Sepsis-Induced Acute Kidney Injury by Regulating Macrophage Polarization via the ECM1/STAT5 Pathway

Shionone Attenuates Sepsis-Induced Acute Kidney Injury by Regulating Macrophage Polarization via the ECM1/STAT5 Pathway

BackgroundsTo date, there are no specific drugs approved for the treatment of sepsis associated acute kidney injury (AKI). Shionone is a natural component with anti-inflammatory activity. In this study, we sought to determine the functional role of Shionone in sepsis-induced AKI.MethodsAnimal models...

Full description

Bibliographic Details
Main Authors: Biao Zhang, Yi Xue, Jin Zhao, Huojun Jiang, Jiaoli Zhu, Hao Yin, Yizhen Qiu, Aihao Hu, Lingqi Xu, Yi Song, Xin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Medicine
Subjects:
acute kidney injury
ECM1
macrophages
inflammation
shionone
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.796743/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.796743/full

Similar Items