An adiponectin-S1P autocrine axis protects skeletal muscle cells from palmitate-induced cell death

Abstract Background The prevalence of type 2 diabetes, obesity and their various comorbidities have continued to rise. In skeletal muscle lipotoxicity is well known to be a contributor to the development of insulin resistance. Here it was examined if the small molecule adiponectin receptor agonist A...

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Bibliographic Details
Main Authors: Amy Botta, Kazaros Elizbaryan, Parastoo Tashakorinia, Nhat Hung Lam, Gary Sweeney
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Lipids in Health and Disease
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12944-020-01332-5