LOX upregulates FAK phosphorylation to promote metastasis in osteosarcoma

LOX upregulates FAK phosphorylation to promote metastasis in osteosarcoma

Osteosarcoma is a malignant bone tumor that commonly occurs in the pediatric population. Despite the use of chemotherapy and surgery, metastasis remains to be the leading cause of death in patients with osteosarcoma. We have previously reported that cytoplasmic mislocalization of p27 is associated w...

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Bibliographic Details
Main Authors: Xiang Chen, Margaret Clement, M. John Hicks, Poonam Sarkar, M. Waleed Gaber, Tsz-Kwong Man
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-01-01
Series:Genes and Diseases
Subjects:
Focal adhesion kinase
Lysyl oxidase
Metastasis
Osteosarcoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304222000101

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http://www.sciencedirect.com/science/article/pii/S2352304222000101

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