Deconvolving the roles of Wnt ligands and receptors in sensing and amplification

Abstract Establishment of cell polarity is crucial for many biological processes including cell migration and asymmetric cell division. The establishment of cell polarity consists of two sequential processes: an external gradient is first sensed and then the resulting signal is amplified and maintai...

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Bibliographic Details
Main Authors: Rui Zhen Tan, Ni Ji, Remco A Mentink, Hendrik C Korswagen, Alexander van Oudenaarden
Format: Article
Language:English
Published: Springer Nature 2013-01-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2012.64